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To better assist you with your request, please choose a research area provided by Toxys. In case you cannot find an exact match, simply select any service, and our concierge team will swiftly address it once your request has been submitted.
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Cytotoxicity
Test for effects on cell viability and proliferation
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In Vivo REACH Services
Performing testing when in vitro studies cannot be used to predict biological responses
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OECD 489: In Vivo Mammalian Alkaline Comet Assay
Measure the mitogenic and genotoxic potential of test compounds.
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OECD 474: Mammalian Erythrocyte Micronucleus Test
The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone marrow and/or peripheral blood cells of animals, usually rodents (mice or rats).
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Genotoxicity
Evaluate potential of a compound to cause mutations and chromosomal aberations
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ToxTracker assay
An assay for detection of signaling pathways underlying carcinogenicity/genotoxicity.