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Chemistry, Manufacturing and Controls (CMC)

Request Chemistry, Manufacturing and Controls services
Compound Synthesis

Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Custom Building Blocks

Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
Method Development and Validation

Develop and validate methods for synthesis and scale up of drug candidates.
Chemical Stability

Measure the stability of small molecules in solution.
Impurity Synthesis

Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
Drug Product Stability

Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Building Blocks

Find chemicals used for creating new compound chemotypes and HTS libraries.
Dissolution Profiling

Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Real-time Stability Test

Assure stability and physical integrity of consumer products in real-time conditions.
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