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To better assist you with your request, please choose a research area provided by Sygnature Discovery. In case you cannot find an exact match, simply select any service, and our concierge team will swiftly address it once your request has been submitted.
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Assay Development
Construct or create new assays or modify existing ones.
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Biomarker Discovery
Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
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Solubility Studies
Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
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In Vivo Pharmacokinetics
Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
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Metabolite Identification and Profiling
Estimate drug candidate metabolites after administration of drug to an animal or human subject.
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Cell Based Assays
Apply compounds to cells and test for cellular phenotypes and effects on gene expression
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Compound Synthesis
Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
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Flow Cytometry
Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
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Cell Proliferation
Measure cell number, cell viability and cell division.
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Protein Binding
Determine drug-protein binding interactions
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