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Assay Development

Construct or create new assays or modify existing ones.
Solubility Studies

Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Cell Based Assays

Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cytotoxicity

Test for effects on cell viability and proliferation
Drug Target Assays

Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
Drug Drug Interactions

Determine whether a substance affects the activity of a drug when both are administered together.
Pharmacokinetic Studies

Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Blood Brain Barrier

Measure movement of drugs from circulating blood to brain extracellular fluid.
Membrane Transporters

Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
Membrane Permeability (PAMPA)

Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.
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