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Microbiology

Study microbes and their role in human health.
USP <2022> Microbiological Procedures for Absence of Specified Microorganisms

Determine the absence of objectionable organisms in nutritional supplements.
OECD 489: In Vivo Mammalian Alkaline Comet Assay

Measure the mitogenic and genotoxic potential of test compounds.
USP <2021> Microbial Enumeration Tests

Estimate the total aerobic microbial count, total combined yeast and mold counts, and the presence of bile-tolerant gram-negative bacteria present in nutritional supplements.
OECD 473: In Vitro Mammalian Chromosomal Aberration Test

Assess the ability of the test substance to cause structural chromosomal aberrations in cultured mammalian cells.
OECD 475: Mammalian Bone Marrow Chromosomal Aberration Test

The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese hamsters).