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To better assist you with your request, please choose a research area provided by Organovo. In case you cannot find an exact match, simply select any service, and our concierge team will swiftly address it once your request has been submitted.
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HBS: Human Biological Samples
Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
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Safety Pharmacology
Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
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Metabolic Stability in Hepatocytes
Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
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Metabolic Stability
Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
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Hepatocyte Toxicity
Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
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Inflammatory Bowel Disease Models
Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
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Phase I Metabolism
Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
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Liver Fibrosis Models
Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
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Tubule Epithelial Cell Toxicity
Assess the cytotoxic effects of pre-clinical compounds on the kidney.