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E0143Hu

Human Interleukin 1Β, IL-1B ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed: 10653850). Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6 (PubMed: 12794819).

DETAILS

  • GeneID: 3553
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 30,748
  • Synonyms: Catabolin;IL 1B;IL 1beta;IL-1 beta;IL1B;Interleukin-1 beta
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: IL1B
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 10.07pg/mL
  • Target Protein: IL1B
  • Detection Range: 20-6000pg/mL
  • Full Product Name: Interleukin 1 beta
  • Standard Solution: 8000pg/mL
  • UniProt Accession: P01584