E0143Hu
Human Interleukin 1Β, IL-1B ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed: 10653850). Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6 (PubMed: 12794819).
DETAILS
- Gene Id: 3553
- Uniprot: P01584
- Lead Time: 3 days
- Assay Type: Sandwich
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 10.07pg/mL
- Detection Range: 20-6000pg/mL
- Detection Method: ELISA
- Species Reactivity: Human