(±)5(6)-DiHET lactone

DESCRIPTION

A lactone form of (±)5(6)-DiHET; induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring at 0.01 and 100 pM, respectively; induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner

DETAILS

Inchi: InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18(21)19-16-14-17-20(22)23-19/h6-7,9-10,12-13,18-19,21H,2-5,8,11,14-17H2,1H3/b7-6-,10-9-,13-12-/t18-,19-/m1/s1
Purity: ≥98%
Raptas: Product Type|Biochemicals|Lipids|Hydroxy/Hydroperoxy/Epoxy/Oxo Eicosanoids||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Lipid Biochemistry|Cytochrome P450 Pathways
Smiles: O=C(O1)CCC[C@@H]1[C@H](O)C/C=C\C/C=C\C/C=C\CCCCC
Inchikey: FVXUUVSFGPLNBJ-GMKBZGQBSA-N
Cas Number: 213126-92-2
Formulation: A solution in ethanol
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C20H32O3
Formula Weight: 320.5
Shelf Life Days: 365