EIF5 Blocking Peptide (Center)

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 1983
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: EIF5
Other Names: Eukaryotic translation initiation factor 5, eIF-5, EIF5
Availability: 2 weeks
Bio Background: Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).
Bio References: Si K.,et al.J. Biol. Chem. 271:16934-16938(1996). Wiemann S.,et al.Genome Res. 11:422-435(2001). Ota T.,et al.Nat. Genet. 36:40-45(2004). Bechtel S.,et al.BMC Genomics 8:399-399(2007). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Other Accession: P59325;Q5R4L0;Q07205
Primary Accession: P55010
Targetspecificity: The synthetic peptide sequence is selected from aa 287-298 of HUMAN EIF5