Anti-NUDC Antibody [JE50-74]

DESCRIPTION

NUDC (nuclear distribution gene C homolog, A. nidulans), also known as HNUDC, MNUDC or NPD011, is a ubiquitously expressed protein that is conserved from fungus to human. Highly expressed in proliferating cells, NUDC localizes to the cytoplasm and nucleus, contains a CS domain and participates in neurogenesis, mitosis, nuclear migration and cytokinesis. At the onset of mitosis, NUDC is phosphorylated by Plk. This modification of NUDC is required for proper mitotic spindle formation, chromosome separation during mitosis, cytokinesis and cell proliferation. In neurons and fibroblasts, NUDC forms a complex with LIS1 that localizes to the microtubule network and microtubule-organizing center and facilitates nuclear movement and transport in migrating neurons. In addition, the NUDC/LIS1 complex can associate with the minus-end directed Dynein/Dynactin motor complex and, together, these complexes cooperate in the regulation of cytokinesis.

DETAILS

Host: Rabbit
Type: Primary
Uniprot: SwissProt: Q9Y266 Human;SwissProt: O35685 Mouse;SwissProt: Q63525 Rat
Clone Id: JE50-74
Clonality: Recombinant Rabbit monoclonal Antibody
Conjugate: Non-conjugated
Alias Names: HNUDC antibody MNUDC antibody MNUDC protein antibody NPD011 antibody Nuclear distribution C homolog antibody Nuclear distribution gene C (A.nidulans) homolog antibody Nuclear distribution gene C homolog antibody Nuclear distribution gene C homolog (A. nidulans) antibody Nuclear distribution protein C homolog antibody Nuclear migration protein nudC antibody nudC antibody NudC nuclear distribution protein antibody NUDC_HUMAN antibody OTTHUMP00000004405 antibody SIG 92 antibody SIG92 antibody
Application: WB,IHC-P,FC
Epitope Region: Recombinant protein within Human NUDC aa 207-331 / 331.
Protein Target: NUDC
Target Species: Human,Mouse,Rat
Species Reactivity: Human,Mouse,Rat