mouse monoclonal IgG1; lymphotactin Antibody (E-12) is an IgG1 κ mouse monoclonal lymphotactin antibody (also designated lymphotactin antibody) that detects the lymphotactin protein of mouse, rat and human origin by WB, IP, IF and ELISA. lymphotactin Antibody (E-12) is available as both the non-conjugated anti-lymphotactin antibody form, as well as multiple conjugated forms of anti-lymphotactin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells. Lymphotactin is a C-type member of the chemokine superfamily, but retains only the second and fourth of the four cysteine residues conserved in other chemokines. In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary. Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes. The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.