881-GAT2t 881-GAT2
Promo Available
Anti-GABA Transporter (GAT) 2 Antibody
PhosphoSolutions
DESCRIPTION
Our Anti-GABA Transporter (GAT) 2 primary antibody from PhosphoSolutions is rabbit polyclonal. It detects mouse and rat GABA Transporter (GAT) 2 and is affinity purified. It is great for use in WB, IHC.
DETAILS
- Form: Affinity Purified
- Gene: SLC6A13
- Host: Rabbit
- Rrid: AB_2492120
- Type: Primary Antibody
- Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
- Target: GABA Transporter (GAT) 2
- Isotype: IgG
- Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
- Shipping: Blue Ice
- Synonyms: GABA transport protein antibody, GAT 2 antibody, GAT-2 antibody, GAT2 antibody, GAT3 antibody, S6A13_HUMAN antibody, SLC6A13 antibody, Sodium- and chloride-dependent GABA transporter 2 antibody, Solute carrier family 6 (Neurotransmitter transporter GABA), member 13 antibody, Solute carrier family 6 member 13 antibody
- Clonality: Polyclonal
- Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GAT2, conjugated to keyhole limpet hemocyanin (KLH).
- Expiration: After date of receipt, stable for at least 1 year at -20°C.
- Specificity: Specific for endogenous levels of the ~82 kDa GAT-2 protein.
- Applications: WB, IHC
- Ncbi Gene Id: 171163
- Conjugate Exem: Unconjugated
- Physical State: Liquid
- Quality Control: Western blots performed on each lot.
- Usage Statement: For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
- Molecular Weight: 67
- Production Notes: Prepared from rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.
- Dilution Range Wb: 1:100-200
- Immunogen Species: Rat
- Dilution Range Ihc: 1:100-200
- Species Reactivity: Mouse and Rat
- Target Description: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABA-A receptor (GABA-A-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999)
- Dilution Range Wb Brain: 1:100-200
- Uniprot Number Immunogen Species: P31646
PROMOTION TERMS
Trial Size Available. Limit 1
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