Fenestra VC contrast agent is an iodinated nanoemulsion used for micro-CT imaging of soft tissues. It is a specialized version of Fenestra LC in which the surface of the lipid emulsion particles is modified with DSPE-PEG which blocks the interaction with APO-E thus enabling preclinical angiography by delaying the targeted uptake by hepatocytes of the lipid spheres. Like its liver-selective counterpart, Fenestra VC is eventually metabolized and eliminated through the hepatobiliary system enabling multiple injection longitudinal studies.