15(R)-Lipoxin A4

DESCRIPTION

An aspirin-triggered lipoxin that inhibits LTB4-induced chemotaxis, adherence, and transmigration of the neutrophils with twice the potency of LXA4 demonstrating activity in the nM range

DETAILS

Inchi: InChI=1S/C20H32O5/c1-2-3-8-12-17(21)13-9-6-4-5-7-10-14-18(22)19(23)15-11-16-20(24)25/h4-7,9-10,13-14,17-19,21-23H,2-3,8,11-12,15-16H2,1H3,(H,24,25)/b6-4-,7-5+,13-9+,14-10+/t17-,18-,19+/m1/s1
Purity: ≥95%
Raptas: Product Type|Biochemicals|Lipids|Lipoxins/Resolvin Es||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Specialized Pro-Resolving Mediators||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Lipoxygenase Pathways
Smiles: CCCCC[C@@H](O)\C=C/C=C/C=C\C=C/[C@@H](O)C(O)CCCC(=O)O
Inchikey: IXAQOQZEOGMIQS-JEWNPAEBSA-N
Cas Number: 171030-11-8
Formulation: A solution in ethanol
Storage Temp: -80
Shipping Temp: -80
Formula Markup: C20H32O5
Formula Weight: 352.5
Shelf Life Days: 365