DESCRIPTION

• Tag: Myc-DDK
• Accn: NM_001014006
• Type: Rat Tagged ORF Clone
• Refseq: NM_001014006.1, NP_001014028.1
• Status: 11 Weeks*
• Symbol: F12
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Category: cDNA Clones
• Locus Id: 306761
• Orf Size: 1809 bp
• Synonyms: HAF
• Refseq Orf: 1812 bp
• Uniprot Id: D3ZTE0
• Refseq Size: 2128 bp
• Availability: 11 Weeks
• Cytogenetics: 17p14
• Gene Summary: Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).[UniProtKB/Swiss-Prot Function]
• Sequence Data: ORF Nucleotide Sequence ( show hide ) The ORF insert of this clone is exactly the same as(RR205503).
• Oti Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Oti Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Mammalian Cell Selection: Puromycin