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  • Cas: 956025-83-5
  • Purity: 99.97%
  • Smiles: C(C=1C=2C(N(C(C)(C)C)N1)=NC=NC2N)C3=CC(C)=CC=C3
  • Category: Compound
  • Molecular Weight: 295.38
  • Molecular Formula: C17H21N5


3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifically inhibits analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase with IC50 of 2 μM. 3MB-PP1 can be used for the research of cell division and hypha formation of Candida albicans.

Lead Time: 4 - 5 weeks

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