• Purity: ≥98%
• Synonyms: XAV-939, CHEMBL1086580, 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
• Cas Number: 284028-89-3
• References: Maroof, A. M., Keros, S., Tyson, J. A., Ying, S. W., Ganat, Y. M., Merkle, F. T., ... & Studer, L. (2013). Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell stem cell, 12(5), 559-572. Tian, X. H., Hou, W. J., Fang, Y., Fan, J., Tong, H., Bai, S. L., ... & Li, Y. (2013). XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway. J Exp Clin Cancer Res, 32(100), 9966-32. Liu, C., & He, X. (2010). Destruction of a destructor: a new avenue for cancer therapeutics targeting the Wnt pathway. Journal of molecular cell biology, 2(2), 70-73.
• Application: FA
• Formulation: Crystalline solid
• Chemical Name: 2-[4-(trifluoromethyl)phenyl]-1,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one
• Molecular Weight: 312.3
• Molecular Formula: C14H11F3N2OS
• Storage Conditions: Product should be kept at -20°C.
• Pubchem Openeye Can Smiles: C1CSCC2=C1N=C(NC2=O)C3=CC=C(C=C3)C(F)(F)F

DESCRIPTION