Betulonaldehyde

DESCRIPTION

A pentacyclic triterpenoid; active against P. falciparum (IC50 = 3.36 µg/ml); cytotoxic to NCI H187 and Vero cells (IC50s = 19.23 and 17.09 µg/ml, respectively); reduces TPA-induced ear edema in mice at 1 mg/ear; has also been used a precursor in the semisynthesis of C-2 and C-28 betulonic aldehyde derivatives

DETAILS

Inchi: InChI=1S/C30H46O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h18,20-23,25H,1,8-17H2,2-7H3/t20-,21+,22-,23+,25+,27-,28+,29+,30+/m0/s1
Purity: ≥95%
Raptas: Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products|Terpenes||Research Area|Cancer|Cell Death||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Malaria
Smiles: C[C@]1([C@]2([C@]([C@@]3([C@@](C(C)(C(CC3)=O)C)([H])CC2)C)([H])CC4)C)[C@@]4([H])[C@]([C@@H](CC5)C(C)=C)([H])[C@@]5(C=O)CC1
Inchikey: MHAVMNJPXLZEIG-CNRMHUMKSA-N
Cas Number: 4439-98-9
Formulation: A crystalline solid
Item Origin: Semisynthetic
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C30H46O2
Formula Weight: 438.7
Shelf Life Days: 1460