Anti-Human CD231 FITC (Clone : B2D)

DESCRIPTION

CD231 (TALLA-1, T-ALL-asociated antigen 1), also known as tetraspanin 7, is a 150 kDa (under reducing conditions 32-45 kDa) transmembrane glycoprotein of tetraspanin family, expressed in T-type acute lymphoblastic leukemia, neuroblastoma, and neuronal tissue. Mutations of CD231 gene are associated with X-linked mental retardation, Huntington´s chorea, and myotonic dystrophy. CD231 interacts with integrins and may have a role in the control of neurite outgrowth. Antibodies to CD231 are important for detection of T-ALL and are potential targets of its treatment.Specificity : The mouse monoclonal antibody B2D recognizes an extracellular epitope of CD231 (TALLA-1, tetraspanin 7), a transmembrane glycoprotein expressed in neuronal tissue and T-ALL.

DETAILS

Gene: TSPAN7
App Id: FACS
Antigen: CD231
Gene Id: 7102
Isotype: Mouse IgG1
Clone Name: B2D
Clonality Id: Monoclonal
Conjugate Id: FITC
Purification: The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Reactivity Id: Human
Product Content: Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Alternative Name: TSPAN7, TALLA-1, MXS1, MRX58, TM4SF2,tetraspanin 7
Application Note: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage Condition: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Immunogen Information: Human T-ALL cell line THP-6