mouse monoclonal IgG2a; CEP55 Antibody (B-8) is an IgG2a κ mouse monoclonal CEP55 antibody (also designated CEP55 antibody) that detects the CEP55 protein of human origin by WB, IP, IF and ELISA. CEP55 Antibody (B-8) is available as both the non-conjugated anti-CEP55 antibody form, as well as multiple conjugated forms of anti-CEP55 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. CEP55 (centrosomal protein of 55 kDa), also known as URCC6 (up-regulated in colon cancer 6), is a 464 amino acid protein that localizes to the centrosome during interphase and may be found throughout the cell during mitosis. Widely expressed with highest expression in testis and lower expression in thymus, bone marrow, placenta, fetal heart, digestive tract and several carcinomas, CEP55 exists as a homodimer that interacts with centrosome components and is involved in mitotic exit and cytokinesis. Human CEP55 undergoes several phosphorylation events throughout the cell cycle, most of which are necessary for proper CEP55 function. Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression. Two isoforms of CEP55 are expressed due to alternative splicing events.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.