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E0988Hu

Human Histone Deacetylase 8, HDAC8 ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

DETAILS

  • GeneID: 55869
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 41,758
  • Synonyms: HD8;HDAC 8;HDAC8;Histone deacetylase 8
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: HDAC8
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.055ng/mL
  • Target Protein: HDAC8
  • Detection Range: 0.1-35ng/mL
  • Full Product Name: Histone Deacetylase 8
  • Standard Solution: 40ng/mL
  • UniProt Accession: Q9BY41