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Oritinib mesylate


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  • Purity: 98%
  • Smiles: CS(O)(=O)=O.COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c2CCCCn2c2ccccc12
  • Category: Compounds
  • Cas Number: 2180164-79-6
  • Molecular Weight: 635.78
  • Molecular Formula: C32H41N7O5S


Oritinib (SH-1028) mesylate is a selective, orally active, and pyrimidine-based irreversible inhibitor of EGFR with an IC 50 of 18 nM. Oritinib (SH-1028) mesylate exhibits potent activity against EGFR sensitive and resistant (T790 M) mutations. Oritinib (SH-1028) mesylate significantly inhibits proliferation of tumor cells with EGFR sensitive and resistant mutation.

Lead Time: 4 - 5 weeks

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