DNMT3A Antibody (C-term V897) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 1788
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: DNMT3A
Other Names: DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, MHsaIIIA, DNMT3A
Availability: 2 weeks
Bio Background: CpG methylation is an epigenetic modification that isimportant for embryonic development, imprinting, and X-chromosomeinactivation. Studies in mice have demonstrated that DNAmethylation is required for mammalian development. This geneencodes a DNA methyltransferase that is thought to function in denovo methylation, rather than maintenance methylation. The proteinlocalizes to the cytoplasm and nucleus and its expression isdevelopmentally regulated. Alternative splicing results in multipletranscript variants encoding different isoforms. [provided byRefSeq].
Bio References: Holz-Schietinger, C., et al. J. Biol. Chem. 285(38):29091-29100(2010)Kelemen, L.E., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1822-1830(2010)Park, C.W., et al. J Cardiovasc Transl Res 3(3):290-295(2010)Haggarty, P., et al. PLoS ONE 5 (6), E11329 (2010) :Zhao, Z., et al. J. Biomed. Biotechnol. 2010, 737535 (2010) :
Primary Accession: Q9Y6K1