Scopine (hydrochloride)

DESCRIPTION:

A metabolite of scopolamine; binds to muscarinic acetylcholine receptors (IC50 = 3 µM); selective for muscarinic acetylcholine receptors over nicotinic acetylcholine receptors (IC50 = >500 µM); reduces hyperphagia induced by loxapine and chlorpromazine in C. elegans without affecting basal feeding; improves the blood-brain barrier permeability of chlorambucil when conjugated to chlorambucil

DETAILS

Inchi: InChI=1S/C8H13NO2.ClH/c1-9-5-2-4(10)3-6(9)8-7(5)11-8;/h4-8,10H,2-3H2,1H3;1H/t4-,5-,6+,7-,8+;
Purity: ≥95%
Raptas: Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Neuroscience|Behavioral Neuroscience|Schizophrenia & Psychosis||Research Area|Toxicology & Xenobiotic Metabolism|Drug Metabolites
Smiles: O[C@H]1C[C@H](N2C)[C@@H]3O[C@@H]3[C@H]2C1.Cl
Inchikey: BBBRAOXIMQHVCR-YSJWXMLMSA-N
Cas Number: 85700-55-6
Formulation: A crystalline solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C8H13NO2 • HCl
Formula Weight: 191.7
Shelf Life Days: 1460