Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag (MALS verified)

DESCRIPTION

The Human Epidermal Growth Factor Receptor 2 (HER2) and HER3 form a potent pro-oncogenic heterocomplex upon binding of growth factor neuregulin-1β (NRG1β). The HER2/HER3 extracellular dimer dynamics likely have important implications for modulating receptor activity.

DETAILS

Tag: C-Fc | C-Fc
Host: HEK293
Size: 1mg
Buffer: 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Format: Powder
Purity: 90%
Source: Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag (HE2-H5254) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 652 & Ser 20 - Thr 643 (Accession # P04626 & P21860).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: Her2 & ErbB3
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Thr 23 - Thr 652 & Ser 20 - Thr 643
Swiss-prot: P04626 | P21860
Package Size: 500ug*2
Characteristics: Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag, produced by co-expression of HER2 and ErbB3, has a calculated MW of 95.9 kDa & 94.9 kDa. The protein migrates as 110-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 95.9 kDa & 94.9 kDa
Shipping Condition: RT
Species Reactivity: Human
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