• Purity: ≥98%
• Synonyms: GW 2580, 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine
• Cas Number: 870483-87-7
• References: Conway, J. G., McDonald, B., Parham, J., Keith, B., Rusnak, D. W., Shaw, E., ... & Hutchins, J. T. (2005). Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580. Proceedings of the National Academy of Sciences of the United States of America, 102(44), 16078-16083. Xu, J., Escamilla, J., McBride, W., & Wu, L. (2011). Abstract C227: Blockade of tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor overcomes tumor recurrence after radiation therapy. Molecular Cancer Therapeutics, 10(11 Supplement), C227-C227. Komohara, Y., Hasita, H., Ohnishi, K., Fujiwara, Y., Suzu, S., Eto, M., & Takeya, M. (2011). Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma. Cancer science, 102(7), 1424-1431.
• Application: FA
• Formulation: Crystalline solid
• Chemical Name: 5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine
• Molecular Weight: 366.4
• Molecular Formula: C20H22N4O3
• Storage Conditions: Product should be kept at -20°C.
• Pubchem Openeye Can Smiles: COC1=CC=C(C=C1)COC2=C(C=C(C=C2)CC3=CN=C(N=C3N)N)OC

DESCRIPTION