mouse monoclonal IgG2b; SARP3 Antibody (H-6) is an IgG2b κ mouse monoclonal SARP3 antibody (also designated SARP3 antibody) that detects the SARP3 protein of mouse, rat and human origin by WB, IP, IF and ELISA. SARP3 Antibody (H-6) is available as both the non-conjugated anti-SARP3 antibody form, as well as multiple conjugated forms of anti-SARP3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The frizzled gene was originally identified in Drosophila melanogaster and was shown to be involved in the development of tissue polarity. The mammalian homolog of frizzled as well as several mammalian frizzled-related proteins, FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3 and SARP3 (also designated FRP-5) have been identified. Frizzled is a transmembrane protein that functions as a receptor for Wnt. The frizzled related proteins FRP-1, FRP-2, FRP-3 and SARP3 are secreted proteins that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled. The FRPs/SARPs have also been shown to be involved in the Wnt signaling pathway by regulating the intracellular levels of b-catenin.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.