21123
L-α-Hydroxyglutaric Acid
Cayman Chemical
DESCRIPTION
An α-hydroxy acid; metabolized to α-ketoglutarate by L-2-hydroxyglutarate dehydrogenase; levels are increased in 2-hydroxyglutaric aciduria; inhibits α-ketoglutarate-dependent oxygenases, including several involved in histone lysine and DNA demethylation
DETAILS
- Inchi: InChI=1S/C5H8O5/c6-3(5(9)10)1-2-4(7)8/h3,6H,1-2H2,(H,7,8)(H,9,10)/t3-/m0/s1
- Purity: ≥95%
- Raptas: Product Type|Biochemicals|Small Molecule Inhibitors|Demethylases||Research Area|Endocrinology & Metabolism|Inborn Errors of Metabolism||Research Area|Epigenetics, Transcription, & Translation|Erasers|DNA/RNA Demethylation||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Demethylation||Research Area|Neuroscience
- Smiles: OC(CC[C@H](O)C(O)=O)=O
- Inchikey: HWXBTNAVRSUOJR-VKHMYHEASA-N
- Cas Number: 13095-48-2
- Formulation: A solution in ethanol
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C5H8O5
- Formula Weight: 148.1
- Shelf Life Days: 365