1231125-50mg 1231125-10mg
NS-398
Biogems
DESCRIPTION
NS-398 is a selective inhibitor of the cyclooxygenase-2 enzyme. It is reported to exhibit anti-inflammatory properties with potent analgesic and antipyretic effects.
DETAILS
- Purity: ≥98%
- Synonyms: NS398, NS 398
- Cas Number: 123653-11-2
- References: Futaki, N., Yoshikawa, K., Hamasaka, Y., Arai, I., Higuchi, S., Iizuka, H., & Otomo, S. (1993). NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. General Pharmacology: The Vascular System, 24(1), 105-110. Futaki, N., Takahashi, S., Yokoyama, M., Arai, I., Higuchi, S., & Otomo, S. (1994). NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro.Prostaglandins, 47(1), 55-59. Joki, T., Heese, O., Nikas, D. C., Bello, L., Zhang, J., Kraeft, S. K., ... & Black, P. M. (2000). Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398. Cancer research,60(17), 4926-4931.
- Application: FA
- Formulation: Crystalline solid
- Chemical Name: N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
- Molecular Weight: 314.4
- Molecular Formula: C13H18N2O5S
- Storage Conditions: Product should be kept at room temperature.
- Pubchem Openeye Can Smiles: CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2