Human CD27 / TNFRSF7 Protein, Fc Tag (HPLC verified)

DESCRIPTION

CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.

DETAILS

Tag: C-Fc
Host: HEK293
Size: 200ug
Buffer: 50 mM Tris, 100 mM Glycine, pH7.5
Format: Powder
Purity: 95%
Source: Human CD27, Fc Tag (CD7-H5254) is expressed from human 293 cells (HEK293). It contains AA Thr 21 - Ile 192 (Accession # NP_001233).
Storage: -20℃
Category: Immune Checkpoint Proteins
Molecule: CD27
Accession: NP_001233
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Thr 21 - Ile 192
Swiss-prot: P26842
Package Size: 200ug*1
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.9 kDa. The protein migrates as 53-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 45.9 kDa
Shipping Condition: RT
Species Reactivity: Human
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