Captopril

DESCRIPTION

An ACE inhibitor (IC50 = 23 nM for the rabbit lung enzyme); inhibits contractions in isolated guinea pig ileal segments induced by angiotensin I or bradykinin (IC50s = 23 and 3 nM, respectively); angiotensin I-induced pressor responses in conscious normotensive rats; reduces mean blood pressure in 2K-1C rats and SHRs; reduces HSV-1-induced cytopathogenicity in SH-SY5Y human neuroblastoma cells

DETAILS

Inchi: InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1
Purity: ≥98%
Raptas: Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Small Molecule Inhibitors|Angiotensin-converting Enzyme||Research Area|Cardiovascular System|Cardiovascular Diseases|Heart Failure||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Kidney & Renal Disease|Diabetic Nephropathy||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HSV
Smiles: OC([C@@H]1CCCN1C([C@H](C)CS)=O)=O
Inchikey: FAKRSMQSSFJEIM-RQJHMYQMSA-N
Cas Number: 62571-86-2
Formulation: A crystalline solid
Item Origin: Synthetic
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C9H15NO3S
Formula Weight: 217.3
Shelf Life Days: 1460