Anti-PMS2 Monoclonal Antibody (Clone:IHC412)

DESCRIPTION

Postmeiotic Segregation Increased 2 (PMS2) is a DNA repair protein involved in mismatch repair. Mutations and deficiencies in the PMS2 gene have been linked to microsatellite instability, and malignancies such as hereditary nonpolyposis colorectal cancer and endometrial cancer. Anti-PMS2 is recommended to be used as part of a panel along with antibodies against MLH1, MSH2, and MSH6.

DETAILS

Gene: PMS2
App Id: IHC
Gene Id: 5395
Isotype: Mouse IgG1
Format Id: Purified
Clone Name: IHC412
Uniprot Id: P54278
Host Animal: Mouse
Clonality Id: Monoclonal
Purification: Protein A/G Chromatography
Reactivity Id: Human
Product Content: Tris Buffer, pH 7.3 - 7.7, with 1% BSA and
Alternative Name: PMS2||PMSL2
Application Note: Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.
Storage Condition: Store at 2°C - 8°C. Do not freeze.
Immunogen Information: Recombinant Human PMS2