DESCRIPTION

• Tag: C-10×His
• Host: E. coli
• Size: 100ug
• Buffer: PBS, 0.3 M NaCl, 0.3 M Arginine, pH7.4
• Format: Powder
• Purity: 95%
• Storage: -20℃
• Category: Cytokines&Growth Factors
• Molecule: FGF19
• Accession: NP_005108.1
• Conjugate: Unconjugated
• Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Background: Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs–FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF–FGFR was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.
• Exp Region: Leu 25 - Lys 216
• Swiss-prot: O95750-1
• Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.4 kDa. The protein migrates as 28 kDa under reducing (R) condition (SDS-PAGE).
• Endotoxin Level: 1.0 EU per μg
• Molecular Weight: 23.4 kDa
• Shipping Condition: RT
• Species Reactivity: Human
• Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html