7380-RBP1-P0 7380-RBP1-P1 7380-RBP1-P1ABX
Uroplakin 3A (Bladder Carcinoma Marker) - CloneID -
NeoBiotechnologies
DESCRIPTION
Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
DETAILS
- Host: Rabbit
- Gene ID: 7380
- Uniprot: O75631
- Clonality: Polyclonal
- Gene Name: UPK3A
- Supplied As: 200ug/ml of Ab Purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
- Applications: WB
- Protein Target: UPK3A
- Species Reactivity: Human
- Storage Conditions: Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.