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E6280Hu

Human Tnfaip3-interacting Protein 3, TNIP3 ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

DETAILS

  • GeneID: 79931
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 38,943
  • Synonyms: A20-binding inhibitor of NF-kappa-B activation 3;ABIN-3;LIND;Listeria-induced gene protein;TNFAIP3-interacting protein 3;TNIP3
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: TNIP3
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 7.06ng/L
  • Target Protein: TNIP3
  • Detection Range: 15-3000ng/L
  • Full Product Name: TNFAIP3-interacting protein 3
  • Standard Solution: 3200ng/L
  • UniProt Accession: Q96KP6