GMP Human 4-1BB Ligand Protein, Fc Tag

DESCRIPTION

Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

DETAILS

Tag: N-Fc
Host: HEK293
Size: 100ug
Buffer: PBS, pH7.4
Format: Powder-GMP
Purity: 95%
Source: GMP Human 4-1BB Ligand Protein, Fc Tag (GMP-41LH26) is expressed from human 293 cells (HEK293). It contains AA Arg 71 - Glu 254 (Accession # P41273-1).
Storage: -20℃
Category: Immune Checkpoint Proteins
Molecule: 4-1BB Ligand
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 5 years in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution. Upon receipt, store it immediately at -20°C or lower for long term storage.
Exp Region: Arg 71 - Glu 254
Swiss-prot: P41273-1
Package Size: 100ug*1
Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 87.5 kDa. The protein migrates as 95 kDa±5 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 10 EU/mg
Molecular Weight: 87.5 kDa
Shipping Condition: Blue ice
Species Reactivity: Human
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