Anti-CD3 Monoclonal Antibody (Clone: CA-3)

DESCRIPTION

The alpha-beta heterodimeric T-cell antigen receptor binds antigen in association with major histocompatibility complex proteins on host cell surfaces. These 2 disulfide-linked glycoproteins, TCRA and TCRB are associated on T-cell surfaces with a complex of proteins called CD3(formerly T3). Human CD3 consists of at least 4 proteins: gamma, delta, epsilon, and zeta. The CD3-gamma/CD3-delta gene pair is within 300 kb of the CD3-epsilon gene and therefore these genes form a tightly linked cluster on 11q23. The clustering may be significant in terms of their simultaneous activations during T-cell development.

DETAILS

Gene: Cd3e
App Id: IHC-F
Antigen: T-cell surface glycoprotein CD3 epsilon chain
Gene Id: 315609
Isotype: Mouse IgG1
Clone Name: CA-3
Uniprot Id: D4A5M2
Host Animal: Mouse
Clonality Id: Monoclonal
Purification: Ascites
Reactivity Id: Human
Product Content: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Alternative Name: CD3 antigen, epsilon polypeptide (Predicted) ; Protein Cd3e ; Cd3e ; Cd3e_predicted ; rCG_58471
Application Note: Immunohistochemistry(Frozen Section) : 1µg/ml
Storage Condition: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Immunogen Information: Human thymocytes followed by Sezary T cells.