GMP Human Thrombopoietin Protein

DESCRIPTION

Thrombopoietin (TPO) is a 332 amino acid glycoprotein made primarily in the liver and act as the major physiological regulator of platelet production. TPO binds the TPO receptor, activates JAK and STAT pathways, thus stimulating megakaryocyte growth and platelet production. Additionally, further investigation uncovered that thrombopoietin is a critical cytokine promoting hematopoietic rebound after myeloablation and its transcripts are expressed by multiple cellular sources.

DETAILS

Tag: Native
Host: HEK293
Size: 1mg
Buffer: 20 mM NaAc-HAc, pH5.0
Format: Powder-GMP
Purity: 95%
Source: GMP Human Thrombopoietin Protein (GMP-THNH25) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Gly 353 (Accession # P40225-1).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: Thrombopoietin
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 5 years in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution. Upon receipt, store it immediately at -20°C or lower for long term storage.
Exp Region: Ser 22 - Gly 353
Swiss-prot: P40225-1
Package Size: 50ug*20
Characteristics: This protein carries no "tag". The protein has a calculated MW of 35.5 kDa. The protein migrates as 75 kDa±5 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 10 EU/mg
Molecular Weight: 35.5 kDa
Shipping Condition: Blue ice
Species Reactivity: Human
Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html