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ER1902-61

Scientist.com Supplier

Anti-ATP8A1 Antibody

HuaBio

DESCRIPTION

Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.

DETAILS

  • Host: Rabbit
  • Type: Primary
  • Uniprot: SwissProt: Q9Y2Q0 Human;SwissProt: A0A8I5ZXX6 Rat
  • Clonality: Rabbit polyclonal Antibody
  • Conjugate: Non-conjugated
  • Alias Names: Phospholipid-transporting ATPase IA antibody ATPase class I type 8A member 1 antibody Chromaffin granule ATPase II antibody P4-ATPase flippase complex alpha subunit ATP8A1 antibody ATP8A1 antibody
  • Application: WB,FC
  • Epitope Region: Recombinant protein within Human ATP8A1 aa 410-637 / 1,164.
  • Protein Target: Phospholipid-transporting ATPase IA,ATPase class I type 8A member 1 Chromaffin granule ATPase II P4-ATPase flippase complex alpha subunit ATP8A1,ATP8A1
  • Target Species: Human,Rat
  • Species Reactivity: Human,Rat