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30109

Schisanhenol

Cayman Chemical

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DETAILS

  • Inchi: InChI=1S/C23H30O6/c1-12-8-14-10-16(25-3)21(27-5)20(24)18(14)19-15(9-13(12)2)11-17(26-4)22(28-6)23(19)29-7/h10-13,24H,8-9H2,1-7H3
  • Purity: ≥98%
  • Raptas: Product Type|Biochemicals|Antioxidants||Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products|Lignans||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Glutathione Peroxidase||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Superoxide Dismutase||Research Area|Plant Biology|Phytoprotectants
  • Smiles: COC(C(OC)=C1)=C(O)C2=C1CC(C)C(C)CC3=C2C(OC)=C(OC)C(OC)=C3
  • Inchikey: FYSHYFPJBONYCQ-UHFFFAOYSA-N
  • Cas Number: 69363-14-0
  • Formulation: A crystalline solid
  • Item Origin: Plant/Fructus Schisandrae
  • Storage Temp: -20
  • Shipping Temp: -20
  • Formula Markup: C23H30O6
  • Formula Weight: 402.5
  • Shelf Life Days: 1460

DESCRIPTION

A lignan with diverse biological activities; completely inhibits iron and cysteine-induced MDA formation in rat liver microsomes at 1 mM; reduces HIV-1 viral titers in H9 T cells (EC50 = 5.7 µM); protective against tobacco mosaic virus (TMV) infection in N. glutinosa when applied to leaves from 0.15-0.5 mM; prevents scopolamine-induced increases in hippocampal MDA and AChE levels and decreases hippocampal SOD and GPX activities, as well as increases time spent in the target quadrant in the Morris water maze in mice at 10, 30, or 100 mg/kg