TRMT5 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 57570
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: TRMT5
Other Names: tRNA (guanine(37)-N1)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03152}, 211228 {ECO:0000255|HAMAP-Rule:MF_03152}, M1G-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03152}, tRNA [GM37] methyltransferase {ECO:0000255|HAMAP-Rule:MF_03152}, tRNA methyltransferase 5 homolog {ECO:0000255|HAMAP-Rule:MF_03152}, TRMT5 {ECO:0000255|HAMAP-Rule:MF_03152}
Availability: 2 weeks
Bio Background: tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine.
Bio References: Brule,H., Biochemistry 43 (28), 9243-9255 (2004)
Primary Accession: Q32P41
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP6746b was selected from the C-term region of human TRMT5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.