Biotinylated Cynomolgus CD6 Protein, His,Avitag™ (MALS verified)

DESCRIPTION

CD6 (Cluster of Differentiation 6) is a cell surface glycoprotein that is involved in T cell activation and a member of the scavenger receptor cysteine rich protein superfamily (SRCRSF). CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subset of B cells, and a subset of neuronal cells express CD6. CD6 appears to play a role as both a costimulatory molecule in T cell activation and as an adhesion receptor. Studies demonstrating a mitogenic effect for T cells with some CD6 specific monoclonal antibodies, in conjunction with either accessory cells or PMA and anti-CD2 mAb, support the concept of CD6 as a co stimulatory molecule.

DETAILS

Tag: C-10×His & C-Avi
Host: HEK293
Size: 100ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Biotinylated Cynomolgus CD6 Protein, His,Avitag (CD6-C82E3) is expressed from human 293 cells (HEK293). It contains AA His 18 - Leu 399 (Accession # XP_005577746.1).
Storage: -20℃
Category: MABSol® Biotin Labeled Proteins
Molecule: CD6
Conjugate: Biotin-labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: His 18 - Leu 399
Swiss-prot: XP_005577746.1
Package Size: 100ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 44.4 kDa. The protein migrates as 63-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 44.4 kDa
Shipping Condition: RT
Species Reactivity: Cynomolgus
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