T37774
Thielavin A
TargetMol
DESCRIPTION
Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 and the conversion of PGH2 to PGE2 . Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 μM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 μM; Ki = 27.8 μM).
DETAILS
- Cas: 71950-66-8
- Purity: 98%
- Smiles: Cc1cc(O)c(C)c(O)c1C(=O)Oc1c(C)c(C)c(C(=O)Oc2c(C)c(C)c(C(O)=O)c(O)c2C)c(O)c1C
- Category: Compound
- Molecular Weight: 538.549
- Molecular Formula: C29H30O10
Lead Time: Please Inquire
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