Ku (p70/p80) (Nuclear Marker) - CloneID - KU729

DESCRIPTION

Recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. This MAb recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

DETAILS

Host: Mouse
Gene ID: 2547 (p70), 7520 (p80)
Uniprot: P12956, P13010
Clone ID: KU729
Clonality: Monoclonal
Gene Name: XRCC6 (p70), XRCC5 (p80)
Supplied As: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Applications: FLOW, IF
Protein Target: XRCC6 (p70) & XRCC5 (p80)
Species Reactivity: Human, Primates
Storage Conditions: Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.