26135-MSM3-P0 26135-MSM3-P1 26135-MSM3-P1ABX
SERBP1 / PAI-RBP1 - CloneID - SERBP1/3493
NeoBiotechnologies
DESCRIPTION
SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-伪 and may be involved in chromatin remodeling. It also interacts with PGRMC1 and participates in the transduction of Progesterone s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.
DETAILS
- Host: Mouse
- Gene ID: 26135
- Uniprot: Q8NC51
- Clone ID: SERBP1/3493
- Clonality: Monoclonal
- Gene Name: SERBP1
- Supplied As: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Applications: IHC, WB
- Protein Target: SERBP1
- Species Reactivity: Human
- Storage Conditions: Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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