Timegadine

DETAILS

Cas: 71079-19-1
Purity: 98%
Smiles: N(=C(NC1=NC=CS1)NC2CCCCC2)C=3C4=C(N=C(C)C3)C=CC=C4
Category: Compound
Molecular Weight: 365.5
Molecular Formula: C20H23N5S

DESCRIPTION

Timegadine is a competitive inhibitor of COX and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates and in washed rabbit platelets.

Lead Time: 4 - 5 weeks