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DN1-C52H4-100ug DN1-C52H4-1mg

Canine DNAM-1 / CD226 Protein, His Tag (SPR verified)

ACROBiosystems

DESCRIPTION

Canine DNAM-1, His Tag (DN1-C52H4) is expressed from human 293 cells (HEK293). It contains AA Glu 32 - Gln 263 (Accession # E2R115-1).

DETAILS

  • Tag: C-10×His
  • Host: HEK293
  • Size: 100ug
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 95%
  • Storage: -20℃
  • Category: Immune Checkpoint Proteins
  • Molecule: DNAM-1
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
  • Exp Region: Glu 32 - Gln 263
  • Swiss-prot: E2R115-1
  • Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.2 kDa. The protein migrates as 36-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 28.2 kDa
  • Shipping Condition: RT
  • Species Reactivity: Canine
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html