HLP-H82Ef-25ug HLP-H82Ef-200ug
Biotinylated Human HLA-A*02:01&B2M&p53 (HMTEVVRHC) Complex Protein (Monomer, MALS verified)
ACROBiosystems
DESCRIPTION
TP53 has been recognized as a tumor suppressor. 50% of cancers carry a TP53 mutation while many others affect other pathway components. High-copy numbers of WT p53 peptide-MHC class I complexes were detected on tumor cells as compared to low copies on normal cells. The Human HLA-A*0201 p53 (HMTEVVRHC) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and HMTEVVRHC peptide of the p53.
DETAILS
- Tag: C-10×His & C-Avi
- Host: HEK293
- Size: 25ug
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 90%
- Source: Biotinylated Human HLA-A*02:01&B2M&p53 (HMTEVVRHC) Complex Protein (HLP-H82Ef) is expressed from human 293 cells (HEK293). It contains AA Ile 21 - Met 119 (B2M) & Gly 25 - Ile 308 (HLA-A*02:01) & HMTEVVRHC peptide (Accession # P61769-1 (B2M) & AAA59606.1 (HLA-A*02:01) & HMTEVVRHC).
- Storage: -20℃
- Category: MABSol® Biotin Labeled Proteins
- Molecule: HLA-A*0201 & B2M & p53 (HMTEVVRHC)
- Conjugate: Biotin-labeled
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Ile 21 - Met 119 (B2M) & Gly 25 - Ile 308 (HLA-A*02:01) & HMTEVVRHC peptide
- Swiss-prot: AAA59606.1 & P61769-1 | HMTEVVRHC
- Package Size: 25ug*1
- Characteristics: Biotinylated Human HLA-A*02:01&B2M&p53 (HMTEVVRHC) Complex Protein is produced by co-expression of HLA and B2M loaded with p53 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 49.3 kDa. The protein migrates as 58-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 49.3 kDa
- Shipping Condition: RT
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html