E6507Hu
Human Rna Polymerase Ii Subunit A C-terminal Domain Phosphatase, CTDP1 ELISA Kit
Bioassay Technology Laboratory
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DESCRIPTION
Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation.
DETAILS
- GeneID: 9150
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 104,399
- Synonyms: CCFDN;CTDP1;FCP1;RNA polymerase II subunit A C-terminal domain phosphatase;TFIIF-associating CTD phosphatase
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: CTDP1
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 9.32ng/L
- Target Protein: CTDP1
- Detection Range: 20-4500ng/L
- Full Product Name: RNA polymerase II subunit A C-terminal domain phosphatase
- Standard Solution: 4800ng/L
- UniProt Accession: Q9Y5B0