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sc-393585 SAMPLE sc-393585

Promo Available Scientist.com Supplier

MSG1 (D-7)

Santa Cruz Biotechnology

DESCRIPTION

mouse monoclonal IgG1; MSG1 Antibody (D-7) is an IgG1 κ mouse monoclonal MSG1 antibody (also designated MSG1 antibody) that detects the MSG1 protein of mouse origin by WB, IP, IF and ELISA. MSG1 Antibody (D-7) is available as both the non-conjugated anti-MSG1 antibody form, as well as multiple conjugated forms of anti-MSG1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Pigmentation is a highly characteristic and distinguishing feature of differentiated melanocytes. Generally speaking, pigmentation decreases with melanoma progression and/or loss of several other differentiated properties of melanocytes. The gene which encodes the MSG1 protein is expressed at high levels in strongly pigmented melanoma cells, but at low levels in weakly pigmented cells, suggesting that MSG1 may be associated with pigmentation. MSG1, also designated CITED1, localizes to the nucleus and only demonstrates expression in melanocytes and testis. The deduced 193 amino acid human MSG1 protein shares 75% sequence homology with mouse MSG1. The MSG1 protein contains a serine/threonine-rich region, and research indicates that a fusion protein containing MSG1 and a DNA-binding domain activates transcription in mammalian cells, the activation of which is dependent upon the acidic domain of MSG1.

DETAILS

  • Host: mouse
  • Type: Primary
  • Uniprot: P97769
  • Clonality: Monoclonal
  • Conjugate: unconjugated
  • Applications: WB, IP, IF, ELISA
  • Mouse Gene Id: 12705
  • Protein Target: MSG1
  • Mouse Gene Name: Cited1
  • Species Reactivity: mouse

PROMOTION TERMS

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.